Table 2.
Characteristics of pre implant MCS recipients with and without EQ-5D-3L data
Pre-Implant Characteristics | Pre implant MCS recipients who completed the EQ-5D n=1190* |
Pre implant MCS recipients who did not complete the EQ-5Dn=369 |
p-value |
---|---|---|---|
Demographic and behavioral characteristics | |||
Age at implant (mean years) | 53.48 | 54.11 | 0.39 |
Male (%) | 77.2 | 80.5 | 0.19 |
Race (% white) | 69.4 | 65.9 | 0.20 |
Married at time of implant (%) | 62.3 | 62.3 | 1.00 |
> high school education (%) | 52.6 | 53.5 | 0.79 |
Currently smoking (%) | 13.2 | 12.0 | 0.59 |
Current alcohol abuse (%) | 15.2 | 18.3 | 0.16 |
Current drug abuse (%) | 2.5 | 3.0 | 0.66 |
Clinical characteristics | |||
Primary cardiac diagnosis (%) | |||
Ischemic cardiomyopathy | 36.1 | 35.0 | 0.68 |
Dilated cardiomyopathy | 49.7 | 56.8 | 0.04 |
Other | 14.2 | 9.2 | 0.01 |
Co-morbidities (%) | |||
Diabetes | 37.9 | 40.1 | 0.46 |
CVA | 8.1 | 5.3 | 0.08 |
Right heart failure (RVEF severe) | 24.3 | 26.3 | 0.60 |
Pre COPD | 12.6 | 14.8 | 0.30 |
NYHA class IV (%) | 79.6 | 71.1 | 0.0014 |
Intra aortic balloon pump (%) | 36.0 | 31.2 | 0.09 |
Ventilator (%) | 9.7 | 4.1 | 0.0007 |
ECMO | 2.4 | 1.4 | 0.21 |
Dialysis | 2.1 | 2.7 | 0.49 |
INTERMACS profile at implant (%) | |||
1 | 18.5 | 11.4 | 0.0014 |
2 | 45.9 | 40.4 | 0.06 |
3 | 19.8 | 25.5 | 0.02 |
4 | 10.7 | 13.0 | 0.21 |
5 | 2.4 | 4.6 | 0.03 |
6 | 1.7 | 3.0 | 0.12 |
7 | 1.0 | 2.2 | 0.0002 |
Device strategy (%) | |||
Bridge to transplant –listed | 46.8 | 48.0 | 0.70 |
Bridge to transplant –likely to be listed | 30.5 | 33.1 | 0.35 |
Bridge to transplant –moderately likely to be listed | 9.9 | 9.2 | 0.69 |
Bridge to transplant –unlikely to be listed | 3.4 | 2.2 | 0.25 |
Destination therapy | 7.9 | 6.5 | 0.38 |
Inotrope therapy (%) | 83.6 | 74.8 | 0.0002 |
Implantable cardioverter defibrillator (%) | 78.7 | 83.0 | 0.07 |
Temporary circulatory support (%) | 12.9 | 11.6 | 0.56 |
MCS = mechanical circulatory support, CAD = coronary artery disease, CVA = cerebrovascular accident, COPD = chronic obstructive pulmonary disease, ECMO = extracorporeal membrane oxygenation
Those patients who were ‘too sick’ have been included in the ‘completed’ column and assigned VAS=0 and physical dimensions as ‘extreme problems’ (i.e., group 1)