Skip to main content
. Author manuscript; available in PMC: 2014 Mar 26.
Published in final edited form as: J Mol Neurosci. 2014 Feb;52(2):202–215. doi: 10.1007/s12031-013-0122-5

Fig 1.

Fig 1

Genotype and phenotypic analysis of CBS+/−-deficient mice model. a Representative genotype image of CBS mice done with specific sets of primers. Heterozygote CBS+/−mice produced two bands of 450 and 308 bp; CBS+/+ mice produced a single band of 308 bp. Lane 1, molecular weight markers; lane 2, CBS+/−heterozygote control; lane 3, CBS homozygote control; lanes 6 and 7, CBS heterozygote (CBS+/−) test sample; lanes 4 and 5, CBS homozygote (CBS+/+) test sample. b Phenotype of the CBS+/−mouse model was confirmed by measuring tissue homocysteine expression with Western blot analysis. c Bar graphs representing data from densitometry of the homocysteine expression, normalized with GAPDH assessed by Bio-Rad software; values are expressed in arbitrary units. Data represented mean±SE from n =5 per group