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. 2013 Oct 8;35(3):1907–1915. doi: 10.1007/s13277-013-1256-3

Table 3.

Results of meta-analysis for XPD Asp312Asn (G312A) polymorphism and breast cancer risk

Comparison Population N Test of association Model Test of heterogeneity
OR 95 % CI P P I 2
A vs. G Overall 12 1.06 0.95–1.18 0.325 R 0 88.5
Others 6 1.08 0.93–1.25 0.341 R 0 85.3
Caucasians 6 1.04 0.89–1.21 0.645 R 0 89.0
AA vs. GG Overall 12 1.06 0.87–1.29 0.591 R 0 77.3
Others 6 1.03 0.78–1.37 0.820 R 0 70.0
Caucasians 6 1.09 0.80–1.47 0.584 R 0 82.2
GA vs. GG Overall 12 1.07 0.96–1.20 0.223 R 0 85.7
Others 6 1.16 0.99–1.36 0.067 R 0 82.0
Caucasians 6 0.99 0.88–1.13 0.836 R 0 82.2
AA vs. GA / GG Overall 12 1.04 0.87–1.24 0.654 R 0.001 66.5
Others 6 0.97 0.75–1.26 0.821 R 0.025 61.0
Caucasians 6 1.12 0.85–1.49 0.423 R 0.001 74.6
AA / GA vs. GG Overall 12 1.06 0.96–1.16 0.273 R 0 87.9
Others 6 1.11 0.97–1.28 0.142 R 0 84.6
Caucasians 6 1.00 0.89–1.14 0.962 R 0 87.1

OR odds ratio, CI confidence interval, F fixed effects model, R random effects model