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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1188–1195. doi: 10.1016/j.ijrobp.2013.12.043

Figure 3. Unfractionated or fractionated RT preceding Ad5-GUCY2C produces similar immunologic and antitumor responses.

Figure 3

(A) Mice challenged with CT26-GUCY2C cells (day 0) were observed (n=10), treated with 8 Gy on day 7 (n=10), or treated with 3.5 Gy on days 7, 10, and 13 (n=10). Irradiated mice received Ad5-GUCY2C on day 14. GUCY2C-specific and Ad5-specific T cell responses (B), tumor cure rates (C), and volumes (D) were similar between unfractionated and fractionated RT treatment groups.