Table 4.
Pt | Classification | Variant | Prior Radiotherapy, 131I Ablations |
Time On Study (weeks) |
Best Response | RAI Scan Obtained (weeks)a |
Result |
---|---|---|---|---|---|---|---|
1 | Papillary | Tall cell variant | RAI x2, EBb | 10 | PD | PD after cycle 3c | -- |
2 | Papillary | Follicular variant | RAI x2, EB | 12 | PD | NDd | -- |
5 | Papillary | Tall cell variant | RAI x3 | 112 | SD | 28, 53, 103 | Neg |
10 | Papillary | RAI x2 | 39 | SD | 36 | Faint | |
11 | Papillary | Tall cell, poorly differentiated | EB only | 3 | PD | PD after cycle 1c | -- |
17 | Follicular | Hürthle cell, poorly differentiated | RAI x1, EB | 33 | SD | 31 | Neg |
18 | Papillary | Tall cell, with Hashimoto’s thyroiditis |
RAI x1, EB | 33 | SD | 14, 30 | Neg |
24 | Papillary | RAI x3 | 3 | NE | Off Study after cycle 1e | -- | |
26 | Follicular | Hürthle cell | RAI x3 | 30 | SD | 16, 31 | Neg |
27 | Follicular | Hürthle cell | RAI x3 | 27 | SD | 14 | Faint |
28 | Papillary | RAI x3, EB | 6 | PD | PD after cycle 2c | -- |
Time when RAI scan obtained after study enrollment.
EB, External Beam radiotherapy also administered
RAI scans were not performed in patients with disease progression.
ND, Not done. Patient with abdominal mass unable to tolerate low iodine diet.
Patient refused further therapy