Table 4.
Daily rate of change in serum lipids (median) and pregnancy outcomes.
| Pregnancy Loss | Preterm Delivery | |||
|---|---|---|---|---|
| Daily Rate of Changes in Serum Lipids (mg/dL per day) | Unadjusted OR (95% CI) | Adjusteda OR (95% CI) | Unadjusted OR (95% CI) | Adjusteda OR (95% CI) |
| Total serum lipids | ||||
| −0.49, 2.52 | Reference | Reference | Reference | Reference |
| −6.43, −0.48 | 1.58 (0.43, 5.80) | 1.66 (0.43, 6.46) | 0.67 (0.10, 4.45) | 0.75 (0.10, 5.43) |
| Total cholesterol | ||||
| −0.12, 0.92 | Reference | Reference | Reference | Reference |
| −2.63, −0.11 | 1.91 (0.53, 6.91) | 2.04 (0.54, 7.67) | 0.79 (0.12, 5.31) | 0.86 (0.12, 6.25) |
| Free cholesterol | ||||
| −0.17, 0.37 | Reference | Reference | Reference | Reference |
| −2.07, −0.16 | 2.66 (0.65, 10.89) | 3.25 (0.72, 4.71) | 2.01 (0.20, 20.00) | 2.00 (0.18, 21.96) |
| Phospholipids | ||||
| −0.26, 1.19 | Reference | Reference | Reference | Reference |
| −5.22, −0.25 | 3.91 (0.82, 18.65) | 4.62 (0.90, 3.75) | 1.54 (0.16, 15.13) | 2.11 (0.20, 22.37) |
| Triglycerides | ||||
| 0.00, 0.99 | Reference | Reference | Reference | Reference |
| −3.07, −0.01 | 7.74 (1.49, 40.26) | 9.02 (1.62, 0.30) | 0.98 (0.15, 6.54) | 1.30 (0.17, 9.82) |
a
Adjusted for maternal BMI (kg/m2) and cigarette smoking (yes/no).
NOTE: Daily rate of lipid change is calculated as (pregnancy measurement – the preconception measurement)/days of pregnancy and is measured in mg/dL per day.