Table 2. Genes identified as up-regulated or down-regulated by RNA-Seq and microarray analysis.
| Regulation | Protein location | Biological functions | Synonyms | RNA-Seq | Microarray |
|---|---|---|---|---|---|
| Up | Extracellular | Related to ECM formation and degradation | LOXL4 | 1.586 5 | 3.174 3 |
| Other functions | SUSD2 | 5.498 1 | 1.918 6 | ||
| NPB | 2.444 6 | 1.974 1 | |||
| Related to osteoblast and osteoclast | TCTA | 1.817 8 | 1.504 | ||
| Related to ECM formation and degradation | LARP6 | 2.004 | 1.735 9 | ||
| Related to immune functions | ZBTB32 | 102.989 1 | 1.608 2 | ||
| Intracellular | Other functions | HCST | 5.070 3 | 1.994 1 | |
| HCP5 | 1.957 2 | 2.169 9 | |||
| UCHL1 | 1.830 2 | 1.636 9 | |||
| MBNL3 | 1.730 4 | 1.573 9 | |||
| ZNF671 | 1.694 1 | 1.503 2 | |||
| ADCY4 | 1.599 1 | 3.774 6 | |||
| RDH5 | 1.595 3 | 1.550 1 | |||
| Down | Intracellular | Related to cell proliferation and apoptosis | KIT | 4.258 5 | 4.790 4 |
| TNFRSF25 | 3.598 5 | 1.562 | |||
| RGS12 | 1.796 5 | 1.527 2 | |||
| RICTOR | 1.721 9 | 1.859 1 | |||
| Other functions | GLRX | 1.822 3 | 1.661 3 | ||
| MAG12 | 1.798 4 | 1.514 9 | |||
| FEM1B | 1.585 7 | 1.672 7 | |||
| IQSEC2 | 1.572 4 | 1.593 7 |
ECM, extracellular matrix; LARP6, La ribonucleoprotein domain family, member 6; LOXL4, lysyl oxidase-like 4; RNA-Seq, RNA sequencing; TCTA, T-cell leukemia translocation-associated gene.