Table 1. Percentages of reduction of Enterococcus faecalis biofilms by alexidine alone and combined with NAC after 1 min of exposure: mean (SD).
E. faecalis ATCC 29212 | E. faecalis D1 | |||
---|---|---|---|---|
ALX concentrations/% | Alone | Combined with NAC | Alone | Combined with NAC |
2 | E | E | E | E |
1 | E | E | E | E |
0.5 | E | E | E | E |
0.25 | E | E | E | E |
0.125 | E | E | E | E |
0.062 5 | E | E | E | E |
0.031 | E | E | E | E |
0.015 6 | E | 99.75 (0.18)a,1 | 99.92 (0.13)a,2 | 99.70 (0.39)a,1,2 |
0.007 8 | 99.46 (0.57)1 | 97.22 (2.00)b,2 | 99.50 (0.48)b,1 | 99.23 (0.50)b,1 |
ALX, alexidine; E: eradication, 100% bacterial kill; NAC, N-acetylcysteine, 100 mg⋅mL−1.
Read vertically, the same letter shows differences not statistically significant.
Read horizontally, the same number shows differences not statistically significant.
E. faecalis ATCC 29212: ALX 0.007 8% vs. ALX 0.007 8%+NAC, P<0.001.
E. faecalis D1: ALX 0.015 6% vs. ALX 0.015 6%+NAC, P=0.104; ALX 0.007 8% vs. ALX 0.007 8%+NAC, P=0.163.