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. 2013 Dec 3;23(7):702–713. doi: 10.1089/scd.2013.0472

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Copyright 2014, Mary Ann Liebert, Inc.

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FIG. 3. — Hypothetical relation of VSELs to other multi/pluripotent stem cells identified in adult bone marrow (BM), peripheral blood (PB), and UCB. (A) VSELs and other multi/pluripotent stem cells identified in hematopoietic tissues are independent populations of stem cells. (B) VSELs are the most primitive small dormant stem cells that on proper activation give rise to expanding other larger multi/pluripotent stem cells. (C) VSELs are the most primitive small dormant stem cells that on proper activation give rise to other larger multi/pluripotent overlapping stem cell populations. We hypothesize that it is the most likely scenario.