Table 4.
Pairwise MFI correlations of 9,604 replicate tests among 7 centers testing Lot 2
| Center | MFI (mean±SD)1 | Pearson correlation coefficient [95% CI2] | ||||||
|---|---|---|---|---|---|---|---|---|
| A | B | C | D | E | F | G | ||
| A | 2903±5234 P = 0.02 vs. F |
1 | 0.975 [.973,.977] | 0.977 [.975,.978] | 0.953 [.950,.955] | 0.975 [.974,.977] | 0.969 [.967,.971] | 0.966 [.963,.968] |
| B | 2877±5141 P = 0.05 vs. F |
1 | 0.986 [.985,.987] | 0.969 [.967,.971] | 0.986 [.985,.987] | 0.980 [.979,.982] | 0.973 [.971,.975] | |
| C | 2535±4648 P <0.001 vs. F |
1 | 0.970 [.968,.972] | 0.991 [.991,.992] | 0.988 [.987,.988] | 0.979 [.977,.980] | ||
| D | 2555±4638 P = 0.001 vs. F |
1 | 0.981 [.980,.982] | 0.971 [.969,.973] | 0.968 [.966,.970] | |||
| E | 2631±4881 P = 0.05 vs. F |
1 | 0.985 [.984,.986] | 0.974 [.972,.975] | ||||
| F | 2754±4879 baseline |
1 | 0.969 [.967,.971] | |||||
| G | 2519±4626 P < 0.001 vs. F |
1 | ||||||
1
For testing average center differences, Center F was set as baseline (see Table 2). P-values were calculated using a random effects regression model, which included 6 dichotomous variables (one for each remaining center A–E and G) and a random component representing replicates of kits and beads.
2
Overall 95% confidence intervals for correlations calculated using Fisher’s z transform and a Bonferroni-adjustment for 21 comparisons.