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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Immunol. 2014 Mar 3;192(7):3156–3165. doi: 10.4049/jimmunol.1301726

Figure 2. Inflammatory and anti-inflammatory chemokine and cytokine responses.

Figure 2

A. Neonatal, young adult, and elderly mice have significant differences in the production of inflammatory and anti-inflammatory cytokine and chemokine responses across all time points after CS sepsis. Significance determined using Two-way ANOVA with Bonferroni multiple comparisons post-hoc test. Symbols placed adjacent to graph titles indicate that age was a significant interaction accounting for a source of variation. Symbols placed within the graph show all significant differences between the age groups for specific cytokine. † = p<0.05. ** = P<0.01. *** = p<0.001. **** = p<0.0001. B. Neonatal cord blood had an attenuated cytokine response compared to adult blood following ex vivo stimulation with LPS across all cytokines studied. † = p<0.05. ** = P<0.01. *** = p<0.001. **** = p<0.0001.