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The typical atrophy in a healthy 63-year-old female participant's brain in a T1 scan, (A) FreeSurfer extracted cortical and subcortical ROI borders overlaid on the T1 scan; (B) FMRI reference image overlaid on (A) after intermodal registration using FLIRT. The dura-matter line and the ventriculars illustrate the accuracy of this registration. ROI, regions of interest; FLIRT, FMRIB's linear image registration tool.
