Table 1.
Characteristics of subjects classified by diagnostic group.
| Characteristics | bvFTD (n = 28) | svPPA (n = 16) | nfvPPA (n = 4) | AD (n = 23) | CBS (n = 12) | NC (n = 19) | F-value(df) |
|---|---|---|---|---|---|---|---|
| Age | 62.4 (8.2)2 | 61.8 (6.7)2 | 62.0 (9.4) | 63.3 (10.3)2 | 66.8 (9.2) | 71.3 (7.5) | 3.681(5, 96) |
| Education | 16.4 (3.0) | 16.9 (3.6) | 16.0 (0) | 16.0 (3.1) | 14.5 (2.0) | 17.6 (3.1) | 1.62(5, 92) |
| Gender (M/F) | 21/7 | 10/6 | 2/2 | 15/8 | 4/8 | 7/12 | χ2(5, N = 96) = 10.531 |
| MMSE (0–30) | 25.9 (4.7) | 25.3 (5.5) | 27.0 (3.6) | 19.9 (6.3)2 | 22.6 (7.1)2 | 29.6 (0.7) | 8.391(5, 96) |
| CDR box score (0–18) | 5.8 (2.9)2 | 4.0 (3.0)2 | 1.8 (2.4) | 4.4 (2.3)2 | 4.3 (3.7)2 | 0.1 (0.2) | 11.351(5, 95) |
| NPI total (0–144) | 38.4 (23.1)2 | 28.3 (19.7)2 | 5.5 (5.5) | 12.9 (13.5) | 22.9 (16.1) | 0.0 (0) | 5.251(7, 72) |
| GDS (0–30) | 8.0 (6.4)2 | 6.1 (3.0) | 3.5 (2.4) | 7.5 (4.8)2 | 11.7 (9.7)2 | 2.1 (2.2) | 2.621(7, 73) |
| IRI-EC score (0–56) | 21.0 (6.6)2 | 20.2 (8.8)2 | 29.5 (4.4) | 28.3 (5.1) | 24.4 (6.4) | 28.8 (3.0) | 5.441(7, 94) |
| IRI-EC discrepancy score | 5.8 (7.1)2 | 7.7 (9.6)2 | −2.0 (3.9) | −1.2 (5.1) | 0.1 (5.5) | −0.8 (4.4) | 4.611(7, 94) |
Positive empathic concern discrepancy scores indicate that the subjects overestimated their level of empathic concern, whereas negative scores indicate that the subjects underestimated their level of empathic concern. F-statistics are derived from general linear models with an alpha level of <0.05. bvFTD, behavioral variant frontotemporal dementia; svPPA, semantic variant primary progressive aphasia (PPA); nfvPPA, nonfluent variant PPA; AD, Alzheimer's disease; CBS, corticobasal syndrome; NC, normal controls; MMSE, Mini-Mental State Examination; CDR, Clinical Dementia Rating; NPI, Neuropsychiatric Inventory; GDS, Geriatric Depression Scale; IRI-EC, Interpersonal Reactivity Index Empathic Concern. Data are mean ± SD.
P < 0.05.
P < 0.05 versus NCs based on post hoc Dunnett-Hsu test.