Table 2.

Neural substrates of one's socioemotional overestimation (n = 69).

Anatomic region	mm3	x	y	z	t-value	β-weight
Main effects (critical threshold: 4.57)
R inferior temporal gyrus	115,864	60	6	−34	6.24	−0.40*
R inferior temporal gyrus	″	46	4	−50	5.78	−0.27
R parahippocampal gyrus	″	24	14	−30	5.56	–
R superior temporal pole	″	36	30	−24	5.55	–
R superior temporal pole	″	30	20	−28	5.52	–
R superior temporal pole	″	28	20	−30	5.50	–
R cerebellum	″	28	−24	−28	5.32	–
R insula	″	42	−4	−10	5.10	–
R fusiform gyrus	″	40	−8	−34	5.01	–
R fusiform gyrus	″	34	−10	−50	5.01	0.27
R medial temporal pole	″	44	20	−40	5.00	–
R inferior orbital gyrus	″	30	21	−25	4.87	–
R parahippocampal gyrus	″	12	−2	−24	4.58	–
R parahippocampal gyrus	″	14	0	−24	4.58	–
L superior temporal pole	3152	−22	10	−28	5.19	–
L fusiform gyrus	″	−18	−8	−40	4.98	–
L fusiform gyrus	″	−30	−36	−14	4.64	−0.41*
Analysis removing potential confounds (critical threshold: 3.24)
R inferior temporal gyrus	3648	54	4	−42	4.28	n/a

Main effects: regions where empathic concern discrepancy score negatively correlated with gray matter volumes, adjusting for age, gender, Mini-Mental State Examination (MMSE), and total intracranial volume (TIV) (corrected for family-wise error [FWE] across the whole brain at a significance level of P < 0.05). Analysis removing potential confounds: regions where empathic concern discrepancy score negatively correlated with gray matter volumes, adjusting for change in empathic concern score, diagnostic groups, age, gender, MMSE, and TIV (P < 0.001, uncorrected). Locations of clusters (mm³) are reported in the MNI reference space. – indicates region did not survive (P < 0.20) the modified backward selection procedure.

^*P < 0.05.