Table 3.

Voxel-based morphometry analyses of empathic concern and affective perspective taking scores in the whole sample (N = 102).

Anatomic region	mm3	x	y	z	t-value
Empathic concern (critical threshold: 4.42)
R mid-insula	105,864	42	6	0	6.01
R inferior orbital gyrus	″	36	19	−20	5.85
R anterior insula	″	37	20	−12	5.60
R superior temporal pole	″	32	20	−24	5.35
R superior orbital gyrus	″	13	18	−22	5.26
L inferior orbital gyrus	″	−14	13	−23	4.64
L superior orbital gyrus	″	−10	21	−24	4.59
L anterior insula	″	−37	21	−7	4.54
Affective perspective taking (critical threshold: 4.47)
R inferior orbital gyrus	149,800	38	18	−20	6.33
R mid-insula	″	38	11	−5	6.16
R superior temporal pole	″	38	19	−22	5.90
R superior temporal pole	″	30	19	−28	5.57
R inferior orbital gyrus	″	30	21	−25	4.94
R medial temporal pole	″	45	13	−29	4.85
R amygdala	″	28	2	−17	4.83
R gyrus rectus	″	10	19	−16	4.81
R parahippocampal gyrus	″	23	9	−27	4.75
R inferior temporal gyrus	″	48	−16	−35	4.70
R superior orbital gyrus	″	11	18	−19	4.61
R fusiform gyrus	″	27	−3	−40	4.53
L parahippocampal gyrus	″	−22	9	−25	5.19
L mid-insula	″	−41	0	1	4.81
L superior temporal pole	″	−32	15	−22	4.76

Both empathic concern score and affective perspective taking score were positively correlated with gray matter volumes, adjusting for age, gender, MMSE, and TIV (P_FWE < 0.05). Overlaps of their neural substrates with the neural substrates of one's socioemotional overestimation are written in bold. Locations of clusters (mm³) are reported in the MNI reference space.