Table 1.
Characteristics of NHS full sample versus genetic study participants.
| Characteristics | Full NHS sample | Genotyped sample |
|---|---|---|
| Sample size | 121,701 | 6989 |
| Age in 1992, mean (SD) | 59.03 (7.28) | 60.19 (6.72) |
| BMI in 1992, mean (SD) | 26.22 (5.12) | 26.70 (5.38) |
| Pack-year smoking in 1992, mean (SD) | 13.54 (19.76) | 13.26 (19.68) |
| Total activity in 1992 (Mets/week), mean (SD) | 18.85 (23.18) | 19.12 (21.74) |
| Age at blood draw, mean (SD) | — | 57.79 (6.76) |
| Self-described Caucasian, N (%) | 98,376 (94.5) | 6797 (97.46) |
| Marital status in 1992, N (%) | ||
| Married | 72,454 (81.24) | 5677 (82.78) |
| Widowed | 9289 (10.42) | 737 (10.75) |
| Divorced/separated | 7416 (8.32) | 439 (6.4) |
| Education, N (%) | ||
| RN | 62,673 (70.49) | 4805 (70.21) |
| Bachelor degree | 17,675 (19.88) | 1369 (20.0) |
| Master degree | 7726 (8.69) | 609 (8.9) |
| Doctoral degree | 834 (0.94) | 61 (0.89) |
| Husband's highest education level, N (%) | ||
| <High school graduate | 4743 (6.34) | 337 (5.66) |
| High school graduate | 29,868 (39.92) | 2408 (40.44) |
| College graduate | 21,974 (29.37) | 1686 (28.31) |
| Graduate school | 18,242 (24.38) | 1524 (25.59) |
| Father's occupation when participants were 16 years old, N (%) | ||
| Blue collar | 56,676 (51.66) | 3071 (49.03) |
| White collar | 42,788 (39.0) | 2490 (39.76) |
| Farmer | 10,248 (9.34) | 702 (11.21) |
| 14-year average depression score, mean (SD) | 1.84 (0.62) | 1.83 (0.65) |
| Missing 14-year average depression score, N | 15,679 | 0 |
| CESD-10 score, mean (SD) | 5.72 (4.15) | 5.76 (4.11) |
| Missing CESD-10 score, N | 47,804 | 1093 |
| CESD-10 ≥10, % | 12.23 | 11.89 |
NHS, Nurses' Health Study; CESD, Center for Epidemiologic Studies Depression Scale—10 items.