Table 2.
SNP | Chr | Position | Allele 1/Allele 2 | Allele 1 frequency | Closest gene | Approx. distance (kb) | Effect | Standard error | P-value |
---|---|---|---|---|---|---|---|---|---|
rs6763048 | 3 | 38656398 | A/G | 0.858 | SCN5A | Intron | −0.076 | 0.016 | 8.42E-07 |
rs93239021 | 14 | 93641863 | T/G | 0.257 | IFI27L1 | 3 | −0.063 | 0.013 | 2.43E-06 |
rs108734471 | 14 | 93642502 | A/T | 0.748 | IFI27L1 | 3.6 | 0.063 | 0.014 | 2.71E-06 |
rs4366580 | 13 | 22333062 | T/C | 0.200 | IPMKP1 | 23 | −0.062 | 0.013 | 3.90E-06 |
rs10512653 | 5 | 36474011 | T/C | 0.150 | RANBP3L | 136 | 0.069 | 0.015 | 4.08E-06 |
rs2529282 | 5 | 5564990 | A/G | 0.345 | KIAA0947 | 21 | 0.052 | 0.011 | 4.43E-06 |
rs17287770 | 3 | 46629429 | C/G | 0.928 | LOC100132146 | −0.096 | 0.021 | 5.69E-06 | |
rs26198552 | 5 | 5557842 | T/C | 0.653 | KIAA0947 | 14 | −0.051 | 0.011 | 7.40E-06 |
rs4266492 | 6 | 40803132 | A/C | 0.950 | LRFN2 | 139 | 0.137 | 0.031 | 7.56E-06 |
rs7182961 | 15 | 60707884 | C/G | 0.749 | TLN2 | 19 | 0.057 | 0.013 | 7.70E-06 |
rs2529302 | 5 | 5562703 | A/C | 0.339 | KIAA0947 | 19 | 0.051 | 0.011 | 8.15E-06 |
rs2529292 | 5 | 5563450 | T/C | 0.339 | KIAA0947 | 20 | 0.051 | 0.011 | 9.13E-06 |
rs26527152 | 5 | 5567517 | A/G | 0.659 | KIAA0947 | 24 | −0.051 | 0.011 | 9.16E-06 |
rs25785142 | 5 | 5574830 | A/G | 0.651 | KIAA0947 | 31 | −0.050 | 0.011 | 9.81E-06 |
GWAS, genome-wide association studies; NHS, Nurses' Health Study; SNP, single-nucleotide polymorphism.
SNPs in linkage disequilibrium with each other (r2 > 0.8) on chromosome 14.
SNPs in linkage disequilibrium with each other (r2 > 0.8) on chromosome 5.