. Author manuscript; available in PMC: 2015 Mar 1.

Published in final edited form as: J Intern Med. 2014 Mar;275(3):214–228. doi: 10.1111/joim.12190

Table 1.

Clinical characterization of mild cognitive impairment (MCI)

Definitions	Original Mayo Clinic [6]	Expanded/Key Symposium [7, 8]	NIA-AA [16]	DSM-5 [15]
Criteria
Self- or informant-reported memory complaint	x
Self- or informant-reported cognitive complaint		x	x	x
Objective memory impairment	x
Objective cognitive impairment		x	x	x
Essentially preserved general cognitive functioning	x
Preserved independence in functional abilities	x	x	x	x
No dementia	x	x	x	x

Core clinical criteria according to major definitions are listed.

NIA-AA, National Institute on Aging-Alzheimers Association workgroup; DSM-V, fifth edition of the Diagnostic and Statistical Manual of Mental Disorders; X: criterion required..