Figure 3. Antibody response to IPV and GVI3000 in different lymphoid organs.
BALB/c mice (10 per group) were primed and boosted i.m. with IPV alone or co-administered with GVI3000. 14 days post-boost, the spleen, popliteal lymph nodes (PLN), and intestine were harvested and cultured. On day 7 the levels of serotype-specific IgG (A) and IgA (B) in culture supernatants were determined. Values represent the mean endpoint dilution ± SEM. Statistical significance, *=p<0.05, **=p<0.01, ***=p<0.001.