Table 2.
Distribution of expression levels of FN-1, ITGA-3, ITGB-5, MMP-2, and MMP-9 ECM genes, with significance levels of P < 0.05, fold change >2.0, and clinicopathological variables associated with genetic tracing by RT-PCR.
| Gene | P value | Fold change | Clinicopathological parameter | Comparison |
|---|---|---|---|---|
| FN-1 | 0.022 | −3.07 | Age (years) | <60 × ≥60 |
| ITGA-3 | 0.016 | 2.58 | TNM | TNM III × TNM I |
| ITGB-5 | 0.04 | −2.11 | Degree of cell differentiation | GII × GI |
| 0.029 | 1.33 | TNM | TNM III × TNM I | |
| MMP-2 | 0.015 | 2.17 | Histological type | Mucinous × tubular |
| 0.04 | −1.2 | Peritumoral lymphocyte infiltration | With × without | |
| 0.039 | −2.11 | Age | >60 × ≤60 | |
| MMP-9 | 0.014 | 1.13 | Histological type | Villous × tubular |