Table 1.
Baseline | Endpoint | |
---|---|---|
Mean age (years) | 61.17 ± 6.18 | |
Anthropometry | ||
Weight (kg) | 113.56 ± 11.53 | 97.18 ± 9.05 |
BMI (kg/m2) | 36.31 ± 3.51 | 31.19 ± 2.6 |
Normal weight (proportion) | 0 | 1 (0.6%) |
Overweight (proportion) | 0 | 48 (30.8%) |
Obese (proportion) | 156 (100%) | 107 (68.6%) |
Waist circumference (cm) | 114.0 ± 8.69 | 102.52 ± 7.93 |
Normal (<94 cm) | 1 (0.6%) | 7 (4.5%) |
Increased (≥ 94 cm) | 155 (99.4%) | 149 (95.5%) |
Diabetic parameters | ||
Fasting glucose (mg/dL) | 128.37 ± 31.63 | 101.55 ± 17.02 |
Fasting glucose (mmol/L) | 7.06 ± 1.74 | 5.59 ± 0.94 |
HbA1c | 8.08 ± 0.9 | 6.14 ± 0.71 |
Other metabolic parameters | ||
Total cholesterol (mg/dL) | 294.85 ± 47.65 | 194.38 ± 16.79 |
Total cholesterol (mmol/L) | 7.64 ± 1.23 | 5.03 ± 0.43 |
HDL cholesterol (mg/dL) | 56.63 ± 19.8 | 67.88 ± 17.34 |
HDL cholesterol (mmol/L) | 1.47 ± 0.51 | 1.76 ± 0.45 |
LDL cholesterol (mg/dL) | 177.84 ± 28.34 | 125.47 ± 33.05 |
LDL cholesterol (mmol/L) | 4.61 ± 0.73 | 3.25 ± 0.86 |
Triglycerides (mg/dL) | 297.05 ± 71.25 | 197.9 ± 23.24 |
Triglycerides (mmol/L) | 3.36 ± 0.81 | 2.24 ± 0.26 |
Systolic blood pressure (mmHg) | 157.03 ± 15.46 | 134.61 ± 10.21 |
Diastolic blood pressure (mmHg) | 93.89 ± 11.67 | 79.0 ± 5.57 |
Pulse pressure | 63.07 ± 10.7 | 55.61 ± 8.62 |
Total cholesterol : HDL ratio | 6.02 ± 2.97 | 3.05 ± 0.78 |
LDL : HDL ratio | 3.61 ± 1.71 | 1.88 ± 0.41 |
CRP (mg/dL) | 3.16 ± 4.12 | 0.72 ± 0.56 |
Liver enzymes | ||
AST | 35.55 ± 13.28 | 23.94 ± 8.77 |
ALT | 39.04 ± 19.38 | 26.08 ± 14.42 |
Testosterone | ||
Testosterone (nmol/L) | 8.9 ± 1.99 | 17.36 ± 1.92 |