Table 5.
Changes in intracellular Ca2+ handling‐related proteins.
| SF | HS | 2G | |
|---|---|---|---|
| Upregulation | |||
| Calsequestrin‐1 | * | * | – |
| Isoform 2B of voltage‐dependent calcium channel subunit α‐2/δ‐1 | * | – | – |
| Parvalbumin α | * | * | – |
| Ryanodine receptor 1, skeletal muscle | * | – | – |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | * | * | – |
| Downregulation | |||
| Calsequestrin‐2 | – | * | – |
| Ryanodine receptor 1, skeletal muscle | – | – | * |
Significant responses of protein expressions to spaceflight (SF), hindlimb suspension (HS), or 2G exposure (2G) are indicated by *P < 0.05; −P > 0.05.