Figure 6.
Effect of DIOA on ISC. Cells were cultivated in the presence of 30 nmol/L dexamethasone at air–liquid interface, mounted into Ussing chambers, and ISC measurements were performed. (A) Time course of representative ISC measurement. DIOA was added to the basolateral compartment. Numbers give concentrations in mol/L. Amil = 30 μmol/L amiloride added to the apical compartment. (B) Bar diagram summarizes measurements as mean ± SEM (DIOA added to the basolateral and amiloride to the apical compartment). (C) Time course of representative ISC measurement. DIOA was added to the apical compartment. Numbers represnt concentrations in mol/L. Amil = 30 μmol/L amiloride added to the apical compartment. (D) Bar diagram summarizes measurements as mean ± SEM (DIOA and amiloride were added to the apical compartment).