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A. Communis extract and its different partition extracts downregulate the expression of MITF, p-CREB, and tyrosinase. The B16F10 cells were treated with different extracts (a) ACM, (b) ACD, (c) ACE, and (d) ACNB. # P < 0.05 indicates significant difference from control in the absence 10 nM of α-MSH; *P < 0.05 indicates significant difference from α-MSH treatment control.
