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. 2014 Mar 27;10(3):e1004222. doi: 10.1371/journal.pgen.1004222

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© 2014 Good et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) The solid black line denotes the boundary separating the interference and background selection regimes, while the dashed lines to the left and right denote lines of constant Nσ and lines of constant λ, respectively. (B) A “slice” of this phase plot for constant NU = 50. The black squares denote the results of forward-time simulations and our coarse-grained predictions are shown in solid red. For comparison, the original structured coalescent is shown in solid blue, while the dashed line gives the prediction from the background selection limit in Eq. (2). (C) A similar “slice” of this phase plot for constant Ns = 10, with inset extended on a log-log scale. As , we approach the asymptotic limit from Ref. [44].

Inline graphic — (A) The solid black line denotes the boundary separating the interference and background selection regimes, while the dashed lines to the left and right denote lines of constant Nσ and lines of constant λ, respectively. (B) A “slice” of this phase plot for constant NU = 50. The black squares denote the results of forward-time simulations and our coarse-grained predictions are shown in solid red. For comparison, the original structured coalescent is shown in solid blue, while the dashed line gives the prediction from the background selection limit in Eq. (2). (C) A similar “slice” of this phase plot for constant Ns = 10, with inset extended on a log-log scale. As , we approach the asymptotic limit from Ref. [44].