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. 2014 Mar 27;10(3):e1004248. doi: 10.1371/journal.pgen.1004248

Figure 9. Partial inhibition of NIMA results in alteration of microtubule dynamics and EB1 behavior.

Figure 9

(A) Kymograph showing that in WT cells (strain: MG395), EB1-CR typically moves unidirectionally towards the cell tip. (B) When NIMA function is partially impaired (strain: MG397), the movement of EB1-CR is altered to give instances of EB1 comets moving away from the cell tip. (D) Microtubule tracks in cells with partial NIMA function bend and push against the cell tip wall, a phenotype not typical of WT cells (C). See also Movie 5 and 6 in supporting material. (E) Model illustrating the effect of partial inhibition of NIMA on microtubule dynamics. Bars, 5 μm.