FIGURE 2:

Tandem repeats of aptamers and double-constrained aptamers. (A) Strength of two-hybrid interactions of tandem repeats of aptamers Perfect and 37 with EB1. It is measured by a quantitative assay for β-galactosidase activity and normalized for cell density (A₄₂₀/A₆₀₀). Bars, SEM (n = 3). (B) Strength of two-hybrid interactions of double-constrained aptamers embedded in thioredoxin with EB1. Bars, SEM (n = 3; except aptamer 37, n = 1). (C) Residues overrepresented among double-constrained EB1 aptamers.