Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Apr 1;25(7):1111–1126. doi: 10.1091/mbc.E13-12-0712

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Joensuu et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

“ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society of Cell Biology.

PMC Copyright notice

FIGURE 2: — Actin depolymerization–induced sheet remnants and uneven ER network distribution are revealed by 3D EM. (A) Control and (B) latrunculin A–treated Huh-7 cells transiently expressing ssHRP-KDEL were chemically fixed, cytochemically stained (dark precipitate), and imaged with SB-EM. (a) Model of the ER network (yellow) and the nuclear envelope (NE; blue), (b) one block face image; (c) a representative fenestrated sheet. Asterisk, area void of ER within unevenly distributed ER network; arrowheads, sheets; arrows, tubules. See Supplemental Videos S1 and S2 for the SB-EM data set and models. Bars, 1 μm (in perspective view [a] apply to center of image).