Figure 1. Effects of chemotherapeutic agents and DNMT inhibitors on cell viability of colorectal cancer cell lines.

The cells were treated singly or in combinations with the indicted doses of the agents for 72; 5-FU, 5-fluorouracil; DAC, decitabine; and ZEB, zebularine. Each point represents the mean ±SD (n = 5), asterisks indicate a significance at P<0.05 for comparison with oxaliplatin or 5-FU alone.