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. 2014 Mar 27;9(3):e92018. doi: 10.1371/journal.pone.0092018

Figure 1. Expression of ILT4 on monocytes from controls and patients with PsA before and after in vitro treatment with CD40L.

Figure 1

(A) Cells were gated for monocytes based on their forward-scatter/side-scatter profile. Controls with isotype matched irrelevant mAbs consistently showed <1% of positive cells. The data represent mean±SD (error bars). MFI values of ILT4 expression in CD40L-stimulated cells were as follows. Freshly isolated monocytes: controls, 44.6±9.8, PsA, 40±12.3, P>0.05. CD40L-monocytes: controls, 97.5±29.8, PsA, 57.1±15, P<0.005. Comparison between means was performed by Student's unpaired t test. All P values are 2-tailed. P values <0.05 were considered significant. (B) Correlation between monocyte ILT4 expression and DAS44. ILT4 expression negatively correlated to DAS44 (P = 0.02). Correlations were evaluated by the Pearson parametric for the univariate analysis.