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. 2014 Mar 27;9(3):e93216. doi: 10.1371/journal.pone.0093216

Table 3. Killing kinetics of cathelicidin-RC1 against E. coli ATCC25922.

Time Colony Forming Units (×103, CFUs/ml)
0 min 10 min 20 min 30 min 45 min 60 min 90 min 120 min 180 min
Cathelicidin-RC1 83±7.9 79±21.2 40±28.1 50±10.1 8±5.6 0±0.0 0±0.0 0±0.0 0±0.0
Meropenem 78±8.7 98±11.7 82±12.1 90±14.9 63±40.7 69±15.5 1±1.7 0.3±0.6 0±0.0
Control 93±8.1 81±20.8 96±10.1 104±30.5 96±42.6 168±17.9 387±20.1 637±115.8 1104±145.7

E. coli ATCC25922 was mixed with samples at concentration of 5×MIC for 0, 10, 20, 30, 45, 60, 90, 120 and 160 mins. The results represent mean values of three independent experiments performed in duplicates. The MICs of cathelicidin-RC1 and meropenem against E. coli ATCC25922 are 4.69 and 0.01 μg/ml, respectively.