Table 4. Logistic Regression Risk Models for [TIMP-2]*[IGFBP7] and Clinical Covariates.
| Reference Risk Model | New Risk Model (addition of [TIMP-2]*[IGFBP7] to reference risk model)4 | |||
| Variable | Odds ratio3 | p-value | Odds ratio4 | p-value |
| Diabetes mellitus | 1.12 (0.15–8.61) | 0.92 | 3.60 (0.10–128.42) | 0.48 |
| APACHE III Score | 1.74 (1.23–2.69) | 0.01 | 2.62 (1.04–6.57) | 0.04 |
| Ejection fraction | 10.05 (0.67–150.72) | 0.09 | 18.76 (0.16–2143.76) | 0.02 |
| Baseline creatinine | 0.06 (0.01–3.074) | 0.16 | 0.02 (0–120.37) | 0.36 |
| X-Clamp time | 1.01 (0.99–1.04) | 0.30 | 0.99 (0.97–1.03) | 0.77 |
| COPD | 40.28 (2.2–737.82) | 0.01 | 30.49 (0.81–1146.64) | 0.07 |
| [TIMP-2]*[IGFBP7] 1 , 2 | Not included in model | 1.72 (1.02–2.91) | 0.04 | |
1
[TIMP-2]*[IGFBP7] was log10 transformed.
2
Odds ratio for [TIMP-2]*[IGFBP7] is modeled for change of 0.1 unit in log10 units.
3
95%-confidence interval given in brackets.
4
Adding [TIMP-2]*[IGFBP7] improves the model significantly (p = 0.001, likelihood ratio test).