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. 2014 Mar 27;9(3):e93544. doi: 10.1371/journal.pone.0093544

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© 2014 Scheinost et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A follow-up, seed-based connectivity analysis was performed using a region in the left putamen detected by coupled-ICD but not by conventional ICD and degree analysis. This region shows significant group interaction (p<0.05, corrected) in the caudate and nucleus accumbens. The subjects analyzed in the seed analysis were not used in the voxel-based analysis, providing additional evidence of coupled-ICD robustness and utility. The green region shows the location of the seed ROI.