‘Top’ view of the ribosome. Ribosomal RNA and proteins are shown in ribbon representation, A-, P- and E-site tRNAs are in surface representation (in purple, green and yellow, respectively). The mRNA (grey) is elongated by modeling, the L7/L12 stalk was fit onto the 70S structure. Figure from Schmeing and Ramakrishnan (Reprinted with permission from ref. 45)