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. Author manuscript; available in PMC: 2015 Mar 26.
Published in final edited form as: Chem Rev. 2014 Jan 9;114(6):3266–3280. doi: 10.1021/cr400313x

Figure 2. Peptide bond formation.

Figure 2

A nascent chain of N amino acids attached via an ester bond to the tRNA in the ribosome P site is transferred to the amino-terminal of the A site tRNA. A peptide bond is formed increasing the length of the nascent chain to N + 1, and leaving a deacylated tRNA. The net reaction is thus breaking an ester bond and forming a peptide bond.