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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Obesity (Silver Spring). 2013 Dec 5;22(4):984–988. doi: 10.1002/oby.20647

Figure 2. R151H, a novel low frequency variant in RNF10 has a non-significant trend for association with PFAT (A) and is associated with maximum childhood z-score (B), and maximum recorded BMI from a longitudinal exam when the subject was non-diabetic and ≥15 years of age (C) with the risk allele modestly increasing the risk for T2D (D).

Figure 2

PFAT: Percent body fat, maximum childhood z score is the highest age and sex adjusted z-score from an exam at age <20yrs. For presentation, the z-scores were sex and age (female, 12yr) standardized to a BMI scale. Maximum recorded BMI is defined as the highest BMI recorded from a longitudinal exam when the subject was non-diabetic and ≥15 years of age.* p values were adjusted for age, sex and nuclear family membership. $ p values were adjusted for age, sex, birth year, nuclear family membership and admixture estimates. p values were adjusted for birth year, nuclear family membership and admixture estimates.