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. Author manuscript; available in PMC: 2015 Mar 26.
Published in final edited form as: Chem Rev. 2014 Jan 8;114(6):3224–3265. doi: 10.1021/cr400496q

Figure 12. Nuclear export of MS2 labeled mRNA in mammalian cells.

Figure 12

(A) MSD plot comparison of the nuclear export (red) relative to cytoplasmic (blue) and nucleoplasmic (green) diffusion. (B) Pseudo-colored time-series of an mRNP (red), marked with a white arrow, during nucleocytoplasmic transport across the nuclear envelope (dotted white line). (C) Stalled (red arrows) MS2 labeled RNA (green) at the nuclear envelope before (left image) and after (right image) ATP depletion. Reprinted with permission from ref. 225. Copyright 2010 Nature Publishing Group.