(A) Simplified Jablonski diagram representing excitation (Ex), fluorescence (Fl)
emission, internal conversion (IC), vibrational relaxation (VR), non-radiative
decay (NR), intersystem crossing (ISC), phosphorescence (Ph) and photobleaching
(PB), and the respective timescales at which these processes occur.
S0, singlet ground state; S1, singlet excited state;
T1, triplet state. (B) A simulated intensity trajectory of a
single molecule with two blinking events (orange arrow) and a single
photobleaching step (dotted grey arrow).