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. 2013 Jun 6;28(2):81–97. doi: 10.7555/JBR.27.20120136

Table 3. Patents related to buccal film/patch.

US Patent No. Inventors Work Reference
20110033541 Myers et al. The invention relates to self-supporting film dosage forms which provide a therapeutically effective dosage. Such compositions are particularly useful for treating narcotic dependence while providing sufficient buccal adhesion of the dosage form. [118]
4900552 Sanvordeker et al. A trilaminate film suitable for prolonged and sustained delivery of an active ingredient in a buccal cavity is disclosed. A hydratable mucoadhesive base layer, a non-adhesive reservoir layer and a water-impermeable carrier film sandwiched between and bonded to the base layer and the reservoir layer are the elements which form the trilaminate film. [119]
20100266669 Meyer et al. This invention has led to the development of single layer oral disintegrating films that have at least two different zones, which consist of nicotine that allows sufficient buccal absorption. [120]
20110033542 Myers et al. The present invention relates to compositions, methods of manufacture, products and methods of use relating to films containing therapeutic actives. The invention more particularly relates to self-supporting dosage forms which provide an agonist acting alone or in combination with a buffer system. [121]
20100063110 Meyer et al. This invention relates to the development of muco-adhesive oral disintegrating film that completely disintegrates in mouth with in one to ten minutes. The film is composed of alkaline substance and API which may be present optionally. [122]
5827525 Liao et al. A unidirectional buccal delivery system for the delivery of therapeutic agents over an extended period of time. The delivery system includes a matrix for releasing the drug into the oral cavity at a sustained rate and a means for securing the matrix to the palate or other adequate regions in the oral cavity. [123]
5750134 Scholz et al. A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. A bioadhesive composition that adheres suitably to a mucosal surface and is capable of delivering drugs in sustained fashion, and a patch comprising the bioadhesive composition. [124]