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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: Medicina (Kaunas). 2012;48(8):404–409.

Table 3.

Genotypic Distribution of MMP-3 Gene Polymorphism and Allele Frequencies in the Study Population With and Without ARMD Versus the Control Group

Genotype ARMD Group Non-ARMD Group Control Group P
5A/5A 54 (24.2) 77 (28.7) 144 (25.7) NS
5A/6A 117 (52.5) 139 (51.9) 276 (49.3) NS
6A/6A 52 (23.3) 52 (19.4) 140 (25.0) NS

Allele frequency
5A 0.50 0.55 0.50 NS
6A 0.50 0.45 0.50 NS

Values are number (percentage)

5A or 6A allele frequency was calculated as follows: (2×percentage of 5A/5A or 6A/6A genotype frequency+1×percentage of 5A/6A genotype frequency)/200.

ARMD, age-related macular degeneration; NS, not significant.