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Emerging Biomarkers
| Purpose | Biomarker |
|---|---|
| Marker of amyloid pathology in AD | Plasma Aβ42 |
| Marker of synapse dysfunction and neurodegeneration in AD | CSF VILIP-1 Hydrogen 1 MR spectroscopy Functional MRI Diffusion tensor imaging Magnetic resonance perfusion |
| Marker of oxidative stress and inflammation | CSF Isoprostane CSF interleukins and growth factors CSF S-100B and GFAP CSF YKL-40 |
| Lipidomics | Serum ceramides |
| Marker of Non-AD process | CSF α-synuclein CSF neurofilament CSF TDP-43 |
