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Preformed natural antibody damaged the podocytes. Proliferation of podocytes that were incubated with baboon serum before (pre) or after (post) adsorption on GalTKO PBMCs. Controls included medium with rabbit complement (comp) only (orange bar), baboon serum (preabsorption) without rabbit complement (yellow bar), untreated cells (medium only, white bar), and Nonidet P-40 (NP40)–treated podocytes (gray bar).
