Table 1.
Variable | Control (n=18) | Treated (n=6) | P Value |
---|---|---|---|
Pretreatment B cell counts (cells/μl) | 1066.4±637.8 | 1353.0±1057.9 | 0.55 |
B cell counts in peri-transplant period (cells/μl) | 0.67±1.30 | 0.03±0.08 | 0.06 |
Anti–non-Gal antibody levels before transplant (MFI) | |||
IgG | 7.38±0.65 | 7.97±1.02 | 0.32 |
IgM | 13.32±1.16 | 14.17±2.06 | 0.50 |
Onset of proteinuria after transplant (d) | |||
2+ proteinuriaa | 1.39±0.61 | >12.50±5.54 | 0.004 |
3+ proteinuriab | 8.25±5.69 | 19.75±10.87 | 0.12 |
Control animals did not receive rituximab in peri-transplant period. Treated animals received rituximab in peri-transplant period to prevent post-transplant proteinuria. The data are shown as mean±SD. MFI, mean fluorescence intensity by FACS
Estimated protein concentration is 100 mg/dl.
Estimated protein concentration is 500 mg/dl.