Table 1.
Blood and urine biochemical markers in partial hepatectomized rat
| Marker | After 6 h | After 12 h | After 24 h | |||
|---|---|---|---|---|---|---|
| Sham | PH | Sham | PH | Sham | PH | |
| Blood | ||||||
| pH | 7.43±0.02 | 7.41±0.02 | 7.46±0.01 | 7.45±0.01 | 7.43±0.01 | 7.49±0.01 |
| PCO2 (mmHg) | 48.6±1.9 | 50.0±5.2 | 45.4±2.4 | 41.7±2.5 | 49.0±1.5 | 40.0±2.6 |
| HCO3 (nmol/L) | 31.6±0.7 | 30.3±2.3 | 31.3±1.4 | 28.3±1.6 | 31.7±1.3 | 29.6±1.5 |
| Na+ (nmol/L) | 145.0±0.5 | 144.0±1.5 | 145.6 ±0.8 | 141.7 ±1.2 | 145.7±0.3 | 140.3±2.9 |
| K+ (nmol/L) | 6.6±0.2 | 6.8±0.4 | 5.9±0.2 | 6.8±0.4 | 6.6±0.2 | 5.4±0.5 |
| Ca2+ (nmol/L) | 1.13±0.03 | 1.13±0.05 | 1.21±0.01 | 1.09±0.05 | 1.25±0.02 | 1.17±0.02 |
| Plasma | ||||||
| Pi (mg/dl) | 6.2±0.23 | 5.6±0.18a | 6.4±0.21 | 5.3±0.21a | 6.6±0.2 | 4.4±0.7a |
| Ca (mg/dl) | 8.6±0.31 | 7.8±0.36 | 8.2±0.24 | 7.9±0.37 | 9.0±0.31 | 8.5±0.41 |
| iPTH (pg/ml) | 92.8±9.0 | 253.4± 66.8b | 88.9±33.4 | 114.3±21.8 | 81.0±28.8 | 75.6±26.4 |
| 1,25(OH)2D3 (pg/ml) | 414.7± 28.6 | 552.8± 26.9b | 534.7±81.1 | 706.0±39.6 | 348.8±86.9 | 473.8±85.8 |
| Serum | ||||||
| FGF23 (mg/dl) | 160±5.0 | 150±3.0b | 161±10 | 90±6.0a | 162±10 | 97±6.0a |
| Urine | ||||||
| Pi/Cr | 1.9±0.20 | 2.8±0.33a | 2.3±0.19 | 4.9±0.41a | 2.8±0.41 | 4.6±0.66a |
| Ca/Cr | 0.078±0.030 | 0.076±0.038 | 0.051±0.012 | 0.049±0.006 | 0.037±0.006 | 0.047±0.005 |
| cAMP/Cr (nmol/mg) | – | – | – | – | 262.0±37.1 | 337.5±29.6 |
All data are presented as the mean±SEM (n=12). Blood and urine were collected at the age of 9–10 weeks. Cr, creatinine.
a
P<0.01.
b
P<0.05.