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. 2014 Apr;6(4):375–386. doi: 10.3978/j.issn.2072-1439.2013.11.09

Table 1. Selected studies using FDG-PET for detecting recurrence following SABR.

Study Number of patients Number of recurrences [proportion pathology proven %] SUVmax cutoff Sensitivity (%) Specificity (%) Definition of local recurrence if not biopsied
Essler, et al. (50) 29 6 [NR] 5.48 NR NR Increase in tumor volume of more than 25% on CT, accompanied by metabolic activity in FDG-PET
Bollineni, et al. (49) 132 6 [50] 5.0 NR NR Based on growth by more than 20% of the tumor diameter compared with the pretreatment
Zhang, et al. (47) 128 9 [78] 5.0 100 91 PET/CT
Takeda et al. (48) 154 17 [18] 3.2 (early) 100 96-98 Increase in the cross-sectional tumor size of >25% on successive CT scans at least three times over a 6-month period
4.2 (late)

NR, not reported.