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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: Eur J Cancer Prev. 2011 Sep;20(5):396–402. doi: 10.1097/CEJ.0b013e3283463943

Figure 2.

Figure 2

Identification of SNPs in CD44 exon2 coding region in female breast cancer patients. A, CD44 polymorphisms in CD44 exon2 coding region. Multiple different CD44 polymorphic changes were identified in female breast cancer patients. Synonymous changes were noted bold in red, non-synonymous missense mutations were underlined in red, and the stop codon mutation was underlined and italicized in green. B, Comparison of CD44 polymorphisms in CD44 exon2 coding region between female breast cancer patients and normal donors. Based on the frequency of single nucleotide polymorphisms in CD44 exon2 coding region identified in breast cancer patients, four types of SNPs, SNP-A, SNP-B, SNP-C and SNP-D (from the lowest frequency through the highest frequency), were distinguished (Table 1). Fisher Exact test was used to determine the statistical difference of SNP frequencies between two groups. No significant difference of any SNPs in CD44 exon2 coding region between breast cancer patients and normal donors were found.