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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Curr Opin Oncol. 2014 Jan;26(1):78–85. doi: 10.1097/CCO.0000000000000024

Figure 3. A hypothetical model of differential regulation by p53.

Figure 3

p53 is subjected to a hierarchical sequence of post-translational modifications as stress level increases, which induces various functional outcome depending on the combination of modifications (see text for complete description).