Table 3.

Association Between Baseline Anticholinergic Load and Cognitive Performance (Mean Difference of Cognitive Test Scores, Per One Unit Increase in ACB Score)

	Unadjusted		Adjusted*
Outcome	Mean (SE)	p	Mean (SE)	p
CVLT-II immediate recall (0–36)	−0.16 (0.08)	.04	−0.17 (0.08)	.03
CVLT-II delayed recall (0–9)	−0.04 (0.04)	.29	−0.03 (0.04)	.48
Category fluency	−0.14 (0.05)	.006	−0.12 (0.05)	.02
Verbal fluency	−0.12 (0.06)	.05	−0.11 (0.06)	.07
Trails B	3.91 (2.47)	.11	0.96 (0.22)	.66
3MS†	0.02 (0.02)	.26	0.01 (0.02)	.68
Backward digit span (0–14)	0.02 (0.03)	.50	0.03 (0.03)	.41

Notes :*adjusted for age, race, education, smoking, physical activity, modified Charlson Comorbidity Index, and baseline Mini Mental State Examination score.

†3MS score was transformed by taking the square root of the number of errors.