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. Author manuscript; available in PMC: 2014 Mar 28.
Published in final edited form as: J Biol Chem. 1998 Nov 20;273(47):30847–30850. doi: 10.1074/jbc.273.47.30847

Fig. 4. SRC-1 and GRIP1 potentiate transactivation through the HNF1 gene promoter.

Fig. 4

Expression plasmids that encode SRC-1 (20 μg) or GRIP1 (5 μg) and a reporter construct that contains either the wild type HNF1 gene promoter (2.5 μg) or the promoter that lacks a functional HNF4-binding site (ΔA) (8) were cotransfected into HepG2 cells. Results are presented relative to wild type HNF1 promoter activity in the absence of cotransfection of either SRC-1 or GRIP1 (100%). These results represent the mean ± S.E. of at least three experiments.