Table 4.
Total Inflammatory Cytokine Production (pg/d) by fhRPE After 4 Weeks of Culture
|
Porous Transwell |
Nonporous PCL |
Porous PCL |
|
| EGF | 2.07 ± 0.29 | 0.77 ± 0.29* | 2.08 ± 0.55 |
| Eotaxin | ND | ND | ND |
| FGF-2 | ND | ND | ND |
| CX3CL1, fractalkine | 29.19 ± 4.77 | 20.92 ± 2.40 | 34.36 ± 2.89 |
| G-CSF | ND | ND | ND |
| GM-CSF | ND | ND | ND |
| CXCL1, GRO | 31.26 ± 2.63 | 28.88 ± 1.42 | 26.93 ± 3.46 |
| IL-1α | ND | ND | ND |
| IL-1β | ND | ND | ND |
| IL-1RA | ND | ND | ND |
| IL-6 | 15.21 ± 1.78 | 13.38 ± 0.74 | 12.08 ± 0.97 |
| IL-8 | ND | ND | ND |
| IL-15 | ND | ND | ND |
| IP-10 | ND | ND | ND |
| PDGF-AA | 262.30 ± 9.92 | 245.50 ± 7.93 | 243.30 ± 13.47 |
| PDGF-AB/BB | ND | ND | ND |
| CCL5, RANTES | ND | ND | ND |
| TGF-α | ND | ND | ND |
| TNF-α | ND | ND | ND |
ND, not detected (<2.2 pg/d).
*
P < 0.001 compared to polyester transwells.